ODCs

Click node...

1 OMIM reference -
1 associated gene
7 signs/symptoms

COMMON GENES: 1
COMMON SIGNS: 4

1 OMIM reference -
1 associated gene
8 signs/symptoms

Foveal hypoplasia - presenile cataract

Morning glory syndrome

PAX6

Citations in the biomedical literature:

Foveal hypoplasia - presenile cataract		Morning glory syndrome
	Synonym(s): - O'Donnell-Pappas syndrome		Synonym(s): - Ectasic coloboma - Volubilis syndrome

	Classification (Orphanet): - Rare eye disease - Rare genetic disease		Classification (Orphanet): - Rare eye disease - Rare genetic disease

	Classification (ICD10): - Diseases of the eye and adnexa -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: childhood Average age of death: - Type of inheritance: unknown

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references


COMMON SIGNS	- Cataract / lens opacification - Nystagmus - Optic nerve anomaly / optic atrophy / anomaly of the papilla - Strabismus / squint

Foveal hypoplasia - presenile cataract		Morning glory syndrome
	Very frequent - Anomalies of eyes and vision - Autosomal dominant inheritance - Diffuse / generalised skin hyperpigmentation / melanoderma		Very frequent - Retinitis pigmentosa / retinal pigmentary changes - Visual loss / blindness / amblyopia Occasional - Coloboma of the optic nerve - Retinal detachment